Tramadol Extended-Release
(ER) 100 mg oral tablet or e L010 pill or
is an optimal dosage strength and is ordinarily directed by almost all
certified doctors in the USA in order to efficiently and effectively treat patients
experiencing physical pain. This pharmaceutical medicine may help adults in
providing relief from moderate to severe chronic pain occurring in them.
Typically, this generic pain reliever drug belongs to an Opioids (narcotic
analgesics) drug class and is usually considered to be less potent or efficient
as compared to several opioids.
On 3rd March, 1995, Tramadol
medication was first approved by the Food and Drug Administration (FDA) and is
perfectly suitable for an efficient use in various health conditions like
injury-related pain, post-surgical pain, chronic pain etc. This prescription
medicine is sold in the US market by Ultram, a popular brand name and belongs
to an another class of antidepressant drugs known as serotonin and
norepinephrine reuptake inhibitor (SNRI).
Tramadol Hydrochloride is an
active ingredient drug and health care professionals may prescribe the starting
dose of 100 mg per tablet once in day for the management of moderate to severe
pain. At the beginning, it was first categorized like a non-controlled
property. However, in 2014, it was further re-categorized under Schedule IV of
the Controlled Substances Act (CSA) with some restrictions imposed while
prescribing to patients experiencing chronic pain.
Basic Details of Tramadol
hydrochloride 100mg
Manufacturer’s: Pfizer,
Mylan, Johnson & Johnson, Roche and Teva Pharmaceuticals
Dosage Form Availability:
Oral Tablets ( Immediate-Release and Extended-Release Tablets), Oral Drops,
Oral Capsules, Injections, Effervescent or Carbon Tablets ( Dissolve in H2O and
Release CO2).
Dose & Dosages: Immediate-Release from 50 mg to 400 mg Oral Tablets, Extended-Release from 100 to
300 mg Oral Tablets
Alternative Brand Names:
Ultram, Ultram ER (Extended-Release Tablet Form), Ryzolt, Zytram XL (Tramadol
Hydrochloride Controlled Release Tablets), Conzip and Tramadol HCl (Generic
Form)
Available in Countries:
United States, Australia, Germany, United Kingdom, Brazil, France, Canada and
South Africa
Mechanism of Action
The mechanism of action
about Tramadol medicine is somewhat differ as being compared to other opioids.
In addition, it serves as a dual mechanism related to both an opioid receptor
and reuptake inhibitor. The activation of opioid receptors binds in the brain
as well as spinal cord, like other opioids.
Thus, this interactivity
helps in reducing the sensitivity of pain. Also, the reuptake inhibitor helps
in balancing the activity of two prime neurotransmitters (serotonin and
norepinephrine) in the brain, which in turn further helps in alleviating pain and
contribute to overall well-being.
Therefore, this generic drug
changes the activity of brain signals and central nervous system helps in
perceiving and responding to occurring pain in a patient’s body.
If an initial dose of
Tramadol 100 mg is consumed then it is absorbed in the liver into its active
form, which is more efficient in binding to opioid receptors. The medicine and
its bio-transformation are then urinated
majorly through the kidneys.
Doses & Strength of
Tramadol er 100mg tablet
For effectively treating
patients experiencing chronic pain, the Tramadol is available in form of both
oral disintegrating tablets and capsules to be swallowed with prescribed
minimal doses from 50 mg to 200 mg.
This generic medication is
also available in topical formulations, which includes either creams or gels.
They are effectively used for restricting body pain, which are rarely
prescribed by a doctor and may differ in their efficacy.
50 mg is starting dosage
strength of Tramadol Immediate-Release(IR) oral tablet. In many instances, it
is prescribed to be consumed from 4 to 6 hours as required for relieving
moderate to severe pain in patients.
To provide sudden relief
from chronic pain, 100 mg is the initial dose and dosage of Tramadol
Extended-Release (ER) oral tablet and to be taken by individuals experiencing
pain-related disorder but within 24 hours.
The two significant dosages
of Tramadol ER oral tablets, including 200 mg and 300 mg, which are normally
prescribed once in a day time by health care professionals to alleviate the
pain in patients. They also release the drug slowly as time passes.
The dosages of Tramadol oral
capsules comes in 100 mg and 200 mg, which are used for pain management and to
be taken every 4 to 6 hours as required,
based on the dosage form and individual’s response.
Side Effects of Tramadol 100
mg white pill
If patients take more than
prescribed dosage of Tramadol medicine without doctor’s prescription, they may
lead to the risk of common and serious side effects. Nausea, Vomiting, Dry
Mouth, Dizziness, Drowsiness, Constipation , Headache etc., are common side
effects that may occur in individuals, if misuse, overdose or addicted to this
generic drug.
If people are experiencing
either minor or major symptoms of any pain-related disorder, they may lead to
the risk of some serious side effects such as seizures, serotonin syndrome
(particularly when used with several serotonergic medications), severe allergic
reactions, respiratory depression and so on.
Thus, if these side effects
can occur in patients experiencing moderate or severe pain, they should
instantly consult to a doctor and take according to the prescribed dosages of
Tramadol medicine.
Precautions
Patients do not abruptly
stop taking the usual and prescribed dosages of tramadol drug without doctor’s
prescription, as withdrawal symptoms may occur.
Tramadol generic medicine
should be used cautiously in patients experiencing any severe side effect such
as seizures, or liver and kidney related problems. Also, it can easily be
interacted with several drugs, so it is essential to speak to a doctor once
while taking any other medications.
To overcome the risk of side
effects as well as addiction, Tramadol 100 mg should be used certainly as
prescribed by a healthcare professional.
Overdose of Tramadol drug
may affect to both pregnant women, their unborn child and also while
breastfeeding.
While taking the prescribed
dosages of Tramadol medicine, do not combine with alcohol and other drug
interactions.