Oxycodone ABG 80 mg is made by
utilizing a semi-synthetic opioid, Oxycodone, an analgesic derivative from
Thebaine. Thebaine is a natural alkaloid extracted from papaver somniferum
(poppy seeds) resins. The oxy drug is on the essential medicines list of the WHO
World Health Organization as it is beneficial to relieve moderate to severe
persistent pain when non-opioid remedies and medicines fail. This is regulated
under the Controlled Substances Act Schedule II.
How Does Oxycodone ABG80 function?
Oxy 80 extended-release
works by activating the opioid receptor. It is an agonist(a chemical that works
as a receptor activator) of μ opioid receptor (MOR). It is called extended
release as it is metabolized at a slower speed. After binding Oxycodone with
MOR, a g-protein complex is released resulting in inhibiting the release of
neurotransmitters. That is how it relieves the pain.
Uses of Oxycodone ABG 80:
Oxy pills come in two
release schemes namely immediate release and extended release. Immediate
release is used for acute or chronic moderate to severe pain while extended
release is recommended when the patient requires long-term opioid treatment and
other alternatives are not sufficient.
Medical practitioners and
doctors sometimes recommend oxycodone in combination with naloxone. this
off-label prescription is helpful in severe restless legs syndrome.
Note: Children in the US can
be prescribed oxycodone medicines(oxycontin) for severe pain remedies as it is
approved by the FDA.
Side Effects of Oxycodone ABG 80mg:
The severe side effects of Oxycodone ABG 80mg (oc 80) include trouble in respiration and sleep apnoea(that is
breathing stops or slows down in sleep) but with time almost every side effect
becomes less intense over time. Besides these there are some Common side effects:
Dizziness
Fatigue
Headaches
Lightheadedness
Low blood pressure
Muscle Weakness
Physical dependence
and some least common side
effects are:
Abdominal pain
Diarrhea
Dyspnea
Loss of appetite
Nervousness
Urinary retention
Low libido
Withdrawal Symptoms Of ABG 80 mg
Oxycodone:
Withdrawal Symptoms usually
occur when/if a patient suddenly tries to stop the dosage of medicine. People
using Oxycodone 80 mg for recreational purposes or consuming higher than
prescribed amounts are at higher risk of severe withdrawal symptoms. These symptoms
are panic attacks, Severe pain, insomnia, weakness in muscles, anxiety, muscle
pain, and fever. In many patients, physical dependence has developed due to
continuous intake of Oxycodone ABG 80.
It has also been reported
that newborns show withdrawal symptoms if their mother has been on an oxycodone
prescription.
Precaution of Oxycodone ABG 80:
Oxycodone ABG80 is a slightly
strong dose hence special needs to be taken care of. Here are some precautions
mentioned:
In the case of extended
release, the remedial impact of the pill should be slower than immediate
release so the patient need not swallow the pill directly.
It should not be crushed or
chewed as it will react instantly.
Always taken with water or
other fluids.
Oxycodone ABG 80 pills are an opioid,
semi-synthetic one, thus they should be consumed only by opioid-tolerant
patients.
There is a high probability
of toxicity due to an overdose of this medicine.
Although there is no
evidence of pregnancy-related side effects or adverse impacts still it is not
advisable for pregnant and lactating women.
Interaction of Oxycodone ABG 80:
Like other medicines, Oxycodone ABG 80 mg also has some potential interaction tendencies. Few interactions with other
medicines can impact health adversely while some are mild. The
clearance(excretion from the patient’s body) of Oxycodone can be altered by
mainly two enzymes namely CYP3A4 and CYP2D6. These enzymes are responsible for
metabolism in the case of Oxycodone ABG 80 intake.
CYP3A4 can increase the
half-life of the dose on the other hand, CYP2D6 can decrease the half-life
ultimately impacting the potency of the drug. Fosphenytoin reduces the
analgesic effects of Oxycodone in chronic pain patients by inducing CYP3A4.
Interactions are responsible
for impacting various factors like drug metabolism, sedative activities, etc.
which are explained further:
Drug Metabolism:
Drug metabolism is the
breakdown of drugs by the human body through biochemical transformation.
Interaction of oxycodone 80 mg with other drugs or medicines can result in dose
inefficiency. If metabolism is at a higher rate then it is of less or no use. Similarly,
a lower rate of drug metabolism increases the chances of addiction and
ultimately has more adverse impacts on health than benefits from drugs.
Name of tablets/medicines
resulting in decreased metabolism of Oxycodone ABG 80 mg :
Abiraterone
Acebutolol
Acalabrutinib
Adagrasib
Asunaprevir
Atomoxetine
Bepridil.
Berotralstat
Betaxolol
Name of tablets/medicines
resulting in increased metabolism of Oxycodone ABG80:
Benzatropine
Benzhydrocodone
Abatacept
Adalimumab
Anakinra
Betamethasone
Bimekizumab
Name of tablets/medicines
resulting in severe CNS(central nervous system) depression:
Brexpiprazole
Brexanolone
Apomorphine
Amobarbital
Amitriptylinoxide
Name of tablets/medicines
resulting in reduced serum consumption resulting in reduced efficiency:
Clopidogrel
Ticagrelor
Name of tablets/medicines
resulting in an increase in sedative activities”
Metyrosine
Pramipexole
Propofol
Rotigotine
Ropinirole
Warnings regarding Oxycodone ABG 80:
Since Oxycodone is a natural
alkaloid extracted and utilized as a semi-synthetic analgesic. It is highly
addictive. Even short-term usage can cause and result in many severe health
issues.
Consuming these pills for
recreational, long-term, or overdose can make one physically dependent.
There are the chances of
decreased sex hormone levels. Directly or indirectly impacting sperm production
in men resulting reduction in sperm count.
In women, overdose, abuse,
or without a prescription of Oxycodone ABG 80 mg can disturb the menstrual cycle.
Consciousness of patients
taking these pills can have adverse impacts.
Chances of irregular
heartbeat rhythm and other heart diseases related to blood pressure are
present.
Brain tumor patients are
strictly prohibited from using any opioid substances like Oxycodone.
Doses of Oxycodone ABG 80 can
result in bowel malfunctioning, especially bowel transit. Bowel transit is
defined as the movement of ingested food along the bowel.
Unhealthy esophagus or
esophagus cancer patients are highly vulnerable to severe and life-threatening
consequences.